Acoustic panels will do ZERO for soundproofing. The only thing that works is mass and air. I built my studio to very specific methods and standards. This is the fourth location I've had my studio in and the first purposely built for recording. I tried everything through the years and wasted much time and money until I decided to do it right.
I started with a metal shell. All room framing does not touch this shell at any point. There is a 2" air gap between the room framing and the metal building. The rooms also do not each other at any point. There is a 2" air gap between all rooms.
All rooms have 2 layers of 5/8" X-rated fire rock, even the ceilings. Thus, each wall system between rooms consists of, 1 1/4" fire rock on 2x4 framing (with R-13 insulation) followed by a 2" air gap and the same system repeats for the wall on the other side of the air gap. This makes for a wall system that is roughly 10 1/2" thick. We built custom door frames and hung 1 3/8" solid core doors with 2 doors in each opening. The main interior door coming from outside is 1 3/4" thick. These doors are extremely heavy due to the mass.
All windows between rooms have two panes of glass, one 5/8" thick and one 1/2" thick. This is because being different thicknesses allows them to resonant at different frequencies. The window frames (custom built) also have the same 2" gap between them.
Having said all of that, soundproofing is not for the faint of heart but absolutely essential in my situation. I operate a commercial facility and its imperative that as little sound as possible travels in from outside, outside from inside or from room to room. In my setup the only flanking path for sound to travel is through the slab. If I'd been thinking I'd have poured separate slabs with expansion material between the slab edges.
With this setup I was able to achieve about a 65/70db STL (sound transmission loss) to the outside. To illustrate, a 100db source inside a room would be controlled down to about 30/35 dbs outside the building. And of this 30/35 dbs only low frequencies escape. Mids and highs are virtually silent. And to illustrate the reverse, my lawn service can cut my grass directly against the outside of the building and I don't even know they've been there.
Soundproofing is costly but it's much better to do it properly than to waste time and money over and over when nothing seems to work.
Buy the book Build It Like The Pros. It's a wealth of information.