I have a male (Lou) and a female (Andy). Both really calm and friendly.
The first time Ex-wife came to my apartment, we woke in the morning to find every glass knocked over, and the toilet paper and paper towels shredded. Andy was angry.
When we moved in together, Andy would often walk across the room, stop, hiss at Ex-wife, then keep on walking. Andy HATED her. I just assumed it was a female animal getting jealous.
After we split up, Andy became really friendly with my female guests, and especially my new wife. When I met the new wife, I waved Andy in her face. If Andy hadn't liked her, I may have stopped the relationship!
That cat is a better judge of character than I am. Although they seem to consider me the authority and my wife just a 3rd cat.