With room response, there's no requirement to guess. You can measure the performance at the listening position and know what the response is. Just get a measument mic and a simple, non-colored pre-amp (both inexpensive) and something like Ethan's stepped low frequency sweep SONAR project, and you can easily measure the response.
If you are in a fairly small, rectangular room, even if you have it fairly well treated, it can have significant deviations. If it's not treated, they can be huge. If you don't get the listening position into one of the least worst case places in the room (where the fewest nulls and cancellations at your room's resonances are at), then it'll be even worse.
I'm rearranging my room now, but in the previous configuration, even with a lot of trappage, I had a wicked cancellation centered around 67Hz. It wasn't very wide, but it was deep, and of course that is not an uncommon frequency for the low end of a kick drum, for instance. So I could have a kick drum just pounding like crazy and not hear it, and that frequency is low enough that sanity checking on headphones might not help either. And, since it's a cancellation, something like ARC cannot do anything about it.
I think that my new arrangement will be naturally better in and of itself, then add the trappage back, but I won't know till I measure. I also moved a couple pretty big bookshelves in there and put them directly behind the listening position, with the books shelved pretty randomly wrt to depth/thickness, to help get some diffusion as well. I'll never be able to find the book I'm looking for, but it should make for a pretty good diffusor.