I am mainly a live keyboard player and need to lighten my load (hopefully)... Could someone point me in the direction of an interface to use live with at least 4 (would prefer 6) outputs that functions as a standalone mixer (with that meaning I don't necessarily have to have the computer on to run my hardware keys through it) I know a couple of the MOTU interfaces function in this way but have not found any others. Now I would have really loved one of the usb mixers but don't seem to see any of the smaller ones that have more than a stereo out.... thanks for any recommendations...

The newer mixer+audio interface seems to feature mixing with iPad / Android pad. Taking away the knobs, faders may be a good thing reducing damage from wear and tear.
 
Presonus StudioLive AI-series
Behringer XR18 X-Air (only this model supports USB multi track in/out, the lower model only supports USB stereo)
 
I think the Roland Studio Capture also enables mixing using the device front panel alone. Perhaps a future Roland unit may also feature iPad / Android mixing (just my prediction..).

a lot of them these days will work standalone.  MOTU as you said does.
 
beware of some of the USB mixers.  the older behringer USB mixers were nothing more than a regular mixer with a 2 in/2 out in-line USB "soundcard" which wasn't very good quality to begin with.
 
I know some of the Alesis USB units were that way as well and used USB Codec as their drivers.  very poor and again, only sent the main output from the mixer to 2 channels in the computer/sonar.

the Presonus line can do what you want, but you might have to get the 1818VSL to get enough gozintas and gozoutas.

I'm being told the 1818 has to have a computer and doesn't really run as a standalone mixer, so it's looking like motu is it i guess... thanks everyone

If the number of I/O is sufficient, you can check SPL Crimson.
 

What's not clear to me is why your asking about interfaces and then saying you don't want it to rely on a computer? Is it you want a dual purpose device? A mixer that is also a interface?
ANd most of the better choices will need an iPad , Tablet or laptop to control. That is how they make them inexpensive. By taking away a lot of unessassary hardware and making it all digital you get a lot more bang for the buck. And as said , that also means less stuff to break.
This is the direction mixers are now going. The release of the Behringer air X series is a good example. Lots of ins and outs, lots of DPS power and so many ways to connect. all for $300. But it is only a 2x USB interface, The Air X18 is the multi channel USB but $800.
 
http://www.behringer.com/EN/Products/Xr12.aspx/
 
And even though most interfaces don't advertise the fact, any interface that is not buss powered is technically a stand alone mixer. My Tascam us1641 certainly outputs to the Monitor outputs all but the SPDIF inputs even with my computer turned off. It might even output to 1/2 but I've not tried that.
I'm pretty sure my Scarlett 6i6 outputs to 1/2 without the computer.
 
 

AFAIK, the presonus VSL's effects run as part of its USB driver... it's just asking for trouble.
 
Motu MKIII Hybrid - I have one and it's well worth it. 

Just looked at that Motu-  yes a very good option. Now you got me going too!
I'm looking at something for live . I just bought a TC halicon voice play just to get better effects for my voice. I'm fence sitting about taking it back, just been playing with it for a few hours.. It was $250. For double that the Motu would do a lot more... I could sell my Scarlett 6i6..
 
http://www.sweetwater.com/store/detail/UltraLite3Hy
 
One question on the daw bench test they have the 828 Mk3 listed with very good RTL specs.. Are they the same more or less?
http://forum.dawbench.com/showthread.php?1548-Audio-Interface-Low-Latency-Performance-Data-Base/page13
 
 
 

sock monkey
Just looked at that Motu-  yes a very good option. Now you got me going too!
I'm looking at something for live . I just bought a TC halicon voice play just to get better effects for my voice. I'm fence sitting about taking it back, just been playing with it for a few hours.. It was $250. For double that the Motu would do a lot more... I could sell my Scarlett 6i6..
 
http://www.sweetwater.com/store/detail/UltraLite3Hy
 
One question on the daw bench test they have the 828 Mk3 listed with very good RTL specs.. Are they the same more or less?
http://forum.dawbench.com/showthread.php?1548-Audio-Interface-Low-Latency-Performance-Data-Base/page13
 

 
Pretty Much. Even so, the built-in DSP effects make it a moot point if you're using the unit for tracking - the effects a real-time.