Well the 2.0 and 3.0 cables are different, very different, in fact and you don't want one if you have a 2.0 device. So USB3 has 5 additional pins to provide the high speed full duplex data connection. On the "A" side, the one that goes in to your computer, they are hidden in the back so you don't have an issue. You can plug a 3.0 cable in to a 2.0 port and it works fine (just only at 2.0 speeds) and a 2.0 cable in to a 3.0 port and it works fine (again only at 2.0 speeds). However on the "B" side, the one that goes to your audio card, it is different. The 3.0 cable has an additional part on top with the extra pins in it. So a 3.0 cable won't fit in a 2.0 device.
So, for 2.0 devices, keep using 2.0 cables, regardless of the port you plug them in to on the computer. For USB 3.0 devices you want to get a new cable, because it won't be able to use the higher speeds without it. Of course a USB 3 device should come with a USB 3 cable anyhow.