interpolated
cclarry, the iLok problem is related to my current setup not yours. I never run Windows Update these days as half the changes don't effect what I do. 

See that...and appreciate the feedback I...

I have the latest Insider's Preview version and I assume the iLok is working OK.  I'm not getting any error messages and the few products I still have on iLok were working the last time I checked.   I'll look a little closer and report back later.  I've been "weaning" off of iLok and only have POD Farm 2 that is an often used item on iLok (I have a couple old VST's that I rarely use).  I moved all my Izotope products off of iLok.

Checked my Win 10 Insider version (170424).  I only have one iLok VST installed on this version (An Antares) and it works.  iLok is shown as working OK in Device Manager (under Dongles).  But, I don't have the iLok License Manager installed.  

fireberd
Checked my Win 10 Insider version (170424).  I only have one iLok VST installed on this version (An Antares) and it works.  iLok is shown as working OK in Device Manager (under Dongles).  But, I don't have the iLok License Manager installed.  

Yes...I show the iLok under device manager...but nothing on the iLok works...
iLok Manager doesn't work, East West installation center hangs looking for the
iLok, Pro Tools doesn't work...etc...ad nauseum...

It's seen...it's just non-functional....

There's an update for iLok license manager at the moment but I'm just going to leave it for now. Windows 7 Professional here.
 

Lars,
 
Maybe change the OP title to "Latest Windows Preview Update Kills iLok"?

Hey Larry, since others are running the update with iLok OK, and since you have re-installed iLok already, maybe consider that something in Windows has corrupted?
 
I would at least run the system file checker to see if Windows just needs to replace a corrupted system file.
https://www.howtogeek.com/222532/how-to-repair-corrupted-windows-system-files-with-the-sfc-and-dism-commands/
 
If that doesn't work there is another approach that is a little more extreme, but preserves your data and applications.  It's called the repair installation. https://www.tenforums.com/tutorials/16397-repair-install-windows-10-place-upgrade.html
 
You will only be able to do a repair install of Windows 10 from within Windows 10. You will not be able to do a repair install at boot or in Safe Mode.
 
***** The installation media (ex: ISO or USB) must be the same edition and same or newer build as your currently installed Windows 10. If it's not, then the repair install will fail.
 
There are more notes and warnings included that you should read before attempting this.

I downloaded the iLok License Manager and installed it on my Win 10 Insider Preview version.  It doesn't work on the current preview version (but as previoiusly reported my iLok VST still works).
 
It shows as a 32 bit application and is shown as running in the Task Manager but that is all.  I tried running in compatibility mode for Win 7 and Win 8 and run as Administrator and still will not run.  Fortunately (at least for now) I only have a limited Sonar installed on my Preview version.  I have a separate (different drive) "production" Win 10 system (with Creators Upgrade) and iLok runs OK on it.  

Another thought, never use a "beta" OS as a Production OS.  There can and will be issues.  Its OK to use something such as the Insider Preview OS as long as you have a non beta OS with everything installed.  Basically what I have, my production system and the Insider preview OS, on a separate drive that I dual boot.  I have Sonar and a couple of VST's installed on the Insider preview version and if for some reason I was doing a recording session and something happened I could boot up the Insider preview version and continue the Sonar recording.  I can't fully finish a project but its enough to finish recording.

I didn't want to be the first to come out and say it, so I guess it's safe to mention now ...
 
Backups, backups, backups ...