Just today a PCI to PCI Express adapter arrived that looks like this
https://tinyurl.com/hn7ud3u (though I only paid $12 dollars on Ebay postage-paid from The Netherlands) and, to my astonishment and delight my old
Layla 24 sprung into life. So yes, under Win10 with a questionable-looking adapter in a PCIE slot, it's just okey dokey.
Good luck with yours
David