I'm glad Gary chimed in there.
You have to be very careful when hooking up any 2 devices that have 48 Volt Phantom.
It's almost the safest to use a plain short patch cable un balanced.
One cool thing you can do with the Art is use the line out to your audio interface and use the XLR out and go to a small mixer for monitoring.
That's how I have mine hooked up. I use a Mackie Mix 8 for headphones. I run my 3/4 output from my Scarlett into a stereo channel of ther Mix 8. And then with both my Art and My Joe Meek pre amps they have the extra output running as XLR to the Mix 8 too. I can dial in any level I want. I use the Joe Meek for vocals and the Art for the guitar. My Acoustic has a passive LR Baggs PU and the Art fattens it up along with my Radial Tone Bone.
I go from the Art to the Tonebone using a short patch cord. The Tonebone has all sorts of outputs but I use another short patch cord into my back line input of my interface.
That' s why it's mandatory for me to have the 4 inputs. I can leave everything plugged in.