So, as I have stated in my signature.... I am running windows 7, Sonar X3 producer, and a Studio Live 24.4.2 console, I also have a faderport hooked up  as well.   I have the master bus in sonar routed to the 2 bus -tape return on the studio live, so I typically have to adjust the 2 bus knob to balance the DAW playback with anything else I have going on (like additional mics plugged into the board to record more tracks etc.)   then I control it all with my monitor level knob on the board.
   This past week I was in staples and saw a wireless mouse on sale pretty cheap and grabbed one. 
http://www.staples.com/Lo...M325/product_SS1062476
I figured it might makes things easier in some scenarios...   I had the monitor levels all the way down and still when I took the mouse out of the box, plugged the little receiver into the USB and turned the mouse on there was a pop sound from the speakers (similar to when the computer is changing sample rates like if one project is at 44.1 and the next you open is at 48...)  and then when I clicked play on my project there was asthough the master bus in Sonar was muted but it wasn't?   I only had a couple acoustic tracks and 2 vocals going...  vocals --> master,   guitars --> guitar bus --> master.   I could see the meter on the guitar bus moving,  but there was no activity showing on the master bus and nothing coming out of the speakers at all.  When I moved the volume knob on my board I could hear the encoders in the speakers (kinda sounded like a zipper does)   I removed the USB receiver for the mouse, there was another POP, and then everything worked as normal again.  I plugged my ole wired mouse back in.  
  Is it just THIS mouse?  Is it because it's so cheap?   Do they all conflict with equipment?  

Hi Chuck,
It could be just a bad mouse. I also use a wireless mouse without any issues. Have you tried plugging in the adapter to a different USB port? Also, did you install the latest drivers for the mouse? (I'm just running through the process I had to take).

I have both a Microsoft and a Logitech wireless mice that I use (one at a time) and neither interfere with my USB connected recording interface unit (a Roland Octa-Capture) or any of my control surfaces (and I can have more than one USB connected control surface at a time). 
 
I used to have a Saffire Pro 40 and the wireless mouse did not interfere with that either. 
 
Are you connecting the mouse transceiver directly to a USB port on the PC? or through some external USB hub?  If its directly to the PC, if you have plugged it into a rear USB port, try plugging it into a front USB port.

OK well, my wired mouse is plugged into a USB extension chord (just makes the usb cable a few feet longer) and the back of my computer is a little difficult to access so, I plugged the receiver into the end of the extension cable that is plugged into the rear of my computer,  I had this problem and then tried plugging it in up front, same issue though.

Since you have an ADK computer it may be better to contact them about it.