Here is a quick rundown of my hardware setup.
I have a tower PC.
I have one surge protector plugged into a nearby wall outlet.
Everything is plugged into that: PC, Display, Monitors, External USB HD Power supply, Desk lamp.
Scenario 1: Quad Capture with Hi-Z Off = No hum/buzz whatsoever. No segment lights on at full gain.
Scenario 2: Quad Capture with Hi-Z On = Steady hum/buzzing, Two segment lights on at full gain. Note: Ground lift setting makes no difference.
In contrast, I have a Steinberg CI1 USB interface and using the same usb cable on the same usb port, both Hi-Z and Mic/Line mode sound like Scenario 1.