Wanted to chime in a moment about round-trip latency.
When it comes to round-trip latency, not all units are the same (especially USB audio interfaces).
Yes, the latency from A/D and D/A converters is consistent... as well as the latency from ASIO input and Output buffers (at a given size).
But... the audio interface's driver uses a hidden safety-buffer. This is the X-factor when it comes to audio interfaces.
The best performing drivers use a small hidden safety-buffer (RME, Presonus Audiobox VSL, MOTU).
Tascam USB units are notorious for using a large hidden safety-buffer.
Most drivers don't allow any user control over the hidden safety buffer... so you're SOL if the round-trip latency is high.
12-24ms total round-trip latency is too high to effectively play/record and monitor in realtime thru software EFX/processing.
Get that number down to 5ms... and it's a whole lot more practical.
Round-trip latency is only a factor if you plan to record/monitor in realtime thru software based EFX/processing.
ie: Say you want to track a DI electric bass at 1am... and you want to hear the results (as you're playing) processed thru an AmpSim plugin like Ampeg SVX.
That's when you need low round-trip latency.
If you're not playing/recording and monitoring in realtime thru software based EFX/processing, round-trip latency is not an issue.
Playing soft-synths is dealing with one-way latency (playback)... and is very roughly half the round-trip latency.
If you're buying a new audio interface, IMO it makes sense to get a unit that provides low round-trip latency.
Even if you don't think you'll use it. Six months from now... you may be in a different scenario. If your audio interface has high round-trip latency, there's nothing you can do about it (short of doubling the sample-rate).