You can use WDM/KS driver mode (allows multiple audio interfaces)... and use S/PDIF or Wordclock (from one unit to the other) to make sure there's a single clock source.
IMO, It's not worth the hassle. If you need more inputs (and your audio interface has a Lightpipe input port), it's easier to just get an 8-channel set of converters (Digimax FS, Octa-Pre, ADA-8000) and connect those to the Lightpipe input.