It is my understanding that the picture cache can be deleted, as Sonar will rebuild it. This seems to have fixed some issues for some folks - mostly with redraws, but if it doesn't hurt to do it, it might be worth doing. PLEASE SOMEONE confirm that Sonar will indeed recreate the picture cache after it gets deleted.
Also, If this is a large project that has accumulated a large number of unused audio clips, it might be worth first making a backup of the entire project folder (with its Audio sub-folder), just to make sure you don't lose anything. Then, open the project and do a Save As to a new folder, with the Copy All Audio option checked. This will save the project file to the new location, and will also only copy audio clips that are actually referenced by the project in its current state. This effectively cleans out all the leftover unused clips.
The above two sets of things may or may not fix the current problems, but I think if there is something wrong with the picture cache - which from one of your comments may be the case, then there may be a chance rebuilding the picture cache might help.
And while there may not be anything inherently amiss with a bunch of old non-referenced audio clips, maybe something in there IS getting confused for some reason. Cleaning out the old unused clips might help - IF that is part of the situation. I do not see it as hurting anything.
Maybe some other folks have some thoughts on the above?
Bob Bone