I am using the 2i2 at present. I DO change setting for mixing/recording. 10ms for mixing, 3ms for recording. No issues this way. If I don't, I have problems mixing, and latency issues while recording. I am about to move up to 18i8 for more inputs/outputs and features, but also because of the mixcontrol software, which is not available for 2i2, and the added control over buffer selection that is not available with the 2i2, which is almost the lowest in the food chain.
As others have pointed out, you can adjust manual offset, just like 8.3. The features you are talking about that you have lost, are not lost, dependant upon what interface/software/driver is being used. It's individual to your hardware.
Hope you work it out. You have been given excellent advise above already