I spent most of my playing career standing in front of 1 and sometimes 2 Marshall Super Lead 100 watt stacks. As stated before, playing auditoriums, ball parks, etc. with no mic in the p.a.. Pure brutal volume. You had to stand off to the side a little to escape the ear-bleeding pressure levels!
No, amp sims are not going to re-create that hurricane of sound! But, that's not what it is supposed to do. It's not to take the place of those stacks. It is to try to give you the general impression of a MICED cab. No amp sounds as big in the studio as it does out in the trenches. You play a 4X12 bottom? They mostly cram an SM 56,57, or 58 in to one speaker as close as they can get it. And if you were lucky enough to be in a big enough studio, you might get a mic across the room for distance to fill out the sound. Those huge guitar tracks you hear on most recordings are overdubbed to heck and back! Read some articles on how many guitar tracks Def Leppards guitar slingers had to lay down to get that sound. How about Brian May's world reknowned guitar orchestrations. Reverend Billy Gibbons built a small room out of guitar amps, even with amps pointing down to the floor like a roof for Eliminator! Many tracks with different amps and different guitars is how you arrive at that destination.
I had a hard time with amp sims because I have always been an amp guy. What I found was I had to change my thinking. What I learned was you can take the right amp sim in the right song and by the time you pile on drums, keys, vox, bass, strings, horns, and 3 girls in the background singing "O-O-O-Oh"! no one will hardly ever know the difference. It mimics, not perfectly but most times very well, the sound of 1 or 2 mics on a cab. To get that aura of sound you hear standing in front of the full rig you would have to have 3 dimensional recording techniques coupled with surround sound technology that just is not there today. Maybe in the future. And at the end of the day it made my job easier and faster.
That being said, I'm having a blast going out and sitting in with my buddys. I plug the laptop in to the P.A. or I bring in my HD500. They're still loading gear at the end of the night. It took me all of 5 minutes to pack and I'm already in the car and gone!