The next thing I'm going to try is really twisted but I think it will work.
Well, it sorta worked...what I wanted to do was play all the same note on guitar but with the desired phrasing, thenmove the blobs around to create a melody. However, any interesting melody required moving some blobs to an interval that was out of the "comfort sound" for sound quality. Another issue was all the little resonances and sympathetic vibrations in the guitar, which I'd never really noticed that much before, became transposed and therefore obvious.
However I did experiment some more with transposing chords and doing general transpositions of under a semitone, and it really does work amazingly well with a polyphonic sound sound. I also found out that parts didn't always require a hard attack - some chords that had more of a strummed beginning worked equally well. Slight pitch transpositions also worked well for adding interest to background vocals.
Fun stuff with Melodyne...I gotta upgrade to the Editor version!! The more I use Melodyne, the more I like it.