I'm gonna suggest the following.
I don't think the interface is the best one. It might be cheap.... but the interface is no place to cut corners.
Several issues I see with the interface.
On it's web site, I do NOT see where it has a built in preamp. With dynamic mics, you need something to get the signal level up to a useful level. Either a preamp or a small external mixer will do the job. Next it does not appear to have phantom power for a condenser mic
It also does not have external power....it uses bus power....which on a laptop is probably barely enough to make it work. My Saffire claims to be able to be bus powered as well but it did ship with an external power supply which I use.
It has NO balanced inputs. Only inputs on it are the unbalanced 1/4" style jacks. This is probably where the hum is coming from. The balanced line would help to eliminate the hum, but you do not have that option.
So the combination of unbalanced inputs with no preamps seems to be the issue here.
You mention the latency with synths..... yeah that would be a symptom of a less than ideal interface not set up properly.