Thanks for all the help everyone!
I decided to dig in. Forced a few windows updates that hadn't taken place, updated my video driver, uninstalled some free VSTs I don't use, and did some trouble-shooting on Waves. I was having an issue adding C4 to a project. A Waves tech has been feeding me some things to try. Throughout all this I realized I had my 32bit VST folder in my scan as well as my 64bit VST folder (hence two Waveshell files). I don't think I actually use any 32bit VST files, so I removed that folder and rescanned.
Project is running great (and Sonar is loading a lot faster), but I need to let it idle again tonight and see what happens.
Again, thanks for all the pointers!