I haven't had a chance to work with Melodyn yet but my understanding is it will create a midi event just like we did in the past with Audio snap, correct. The difference should be audio snap could only do one note but Melodyn should create multiple notes, am I still correct?
So once it has done this you'll have to work with them a bit. Change the velocity?
Bass notes are sometimes a problem if they are below the range used by the synth.
Try shifting them up an octave.
Drums you'll have to assign notes that are triggering the correct sound.
I don't understand that your saying you could't edit the notes? Are they not midi now?