Smashing Pumpkins.
I went to see Marilyn Manson but had to stay for Pumpkins afterwards. I never particularly liked them, though I dug a few songs.
Not only was Billy Corgan's voice even more unbearably annoying live, but they played mostly long, atmospheric jams - and the Pumpkins aren't exactly playing on the same level of musicianship as your average prog rock band, so... Basically, 2 hours of agression on the senses.
I got out of there feeling like I needed to hit someone. I couldn't even stay for a drink with our friends afterwards.