Hmmm...I use a Motu pre 4 Usb device...and the latest driver seems to not have output ports labeled right...in the windows control panel/speaker playback devices for me...(for setting win default playback and record in win 7)..it shows output 3/4 and 5/6...there is no 1/2, which has now become 5/6....and there should be no 5/6 output as it only has output 1&2 3&4, and 2 x phones
So yes the driver may be in need of addressing by the backers...I have made a ticket on Motu sight about My issue...if reinstalling the updated driver does not resolve the problem, perhaps reverting back to a older version may solve it..?
But do not stop there, make a ticket with Motu if it continues, and let them know...