Try disabling/re-enabling 64 bit engine in Sonar preferences to see if it makes a difference.
Try enabling/disabling MIDI out for that plugin if it exists (right click the soft synth in the browser).
Create a brand new project in X3D. See if you can reproduce the issue again.
Otherwise I'm thinking you will have to contact these guys:
http://www.lennardigital.com/modules/sylenth1/ Other Sylenth users might want to chirp in and try and reproduce.