I have the same issue using Pod Farm. I get the processed signal only in the left channel and a bypassed signal in the right channel. The work around in the Plug In Manager seems to be a good solution.
My question to you Johannes is how do you unlock Pod Farm? Did you download the software or are you using your hardware and plugging into your computer via USB to unlock it.
The reason I ask this is after reading this thread last night I decided to try and duplicate the problem. I have a Pod pro 3 that unlocks Pod Farm when it is plugged in. After checking out the issue I decided to check the Pod Drivers in the preference section under edit. The Pod 3 is not my main audio interface. I use the VS-100 as the main interface.
I unchecked all the vs-100 drivers in the driver section (ASIO) I tried to check the ASIO drivers for the Pod. It would not allow me to do this. Even after hitting apply. I switched to WDM and it used the wave profiler. I saw the pod and I could select it. I switched back to ASIO. It saw the VS-100 and the Pod 3 pro. I still could not check the Pod unit and use it as an audio interface instead of the VS-100.
I then switched off the VS-100. I was then able to select the Pod as an audio interface. I switched off the Pod and I got the blue screen of death. Major crash dump.
This is the first crash I ever got using the Sonar X series. This is also the first one I got using windows 7. It seems I can plugin the Pod to unlock Pod Farm but when the VS-100 is plugged in I cannot use the Pod as an audio interface using ASIO drivers without unplugging the VS-100.
I wonder if there is a conflict between the Pod 3 drivers and the vst plugs. This is an X3 issue. This did not happen in Sonar 2. I know the limits of ASIO and I am not trying to use two devices at once. I am simply trying to switch from one device to another. This is really no big deal. I can work around it. I just thought it was worth mentioning here.