I got my first Windows 8.1 BSOD yesterday. This immediately pointed to saffire.sys.
I wasn't even running Sonar (software was not installed) and I think it may have happened when Windows triggered a notification sound (just speculation). I am running latest drivers and firmware everywhere (inc Windows update).
Clearly this is an issue to do with the Saffire Pro audio drivers, I've already emailed Focusrite and sent them my crash dump, I await their response.
Please note this was an extremely rare crash so if other Saffire users haven't experienced it yet I'm not surprised, but I'm posting this to here to compare notes with other Saffire users who might have Windows 8.1 issues in the next few weeks/months with Mix Control 3.3.
Cheers
Alex