I picked up Neutron Advanced as part of the Music Production Bundle 2 upgrade from Music Production Bundle 1, which also got me VocalSynth. I already had the RX Plug-in Pack, so that didn't add any value, and I'm not sure how much I'm likely to use VocalSynth, but I'm thinking Neutron Advanced *could* (see below) be worth the $199 upgrade price on its own based on what I saw in the detailed demo video at Sweetwater.com, so, if I find use for VocalSynth, that would just be a bonus.
I have to use "could" at this point, because Neutron has not been stable for me on my system with SONAR Platinum (latest -- i.e. September -- version yet). I'm seeing two problems, both now reported to iZotope.
The first is that quite frequently, when playing through Neutron, especially when changing settings or when using two instances of Neutron (i.e. on different tracks, for example to use the masking features with the symmetric EQ changes), I will hear a brief, very loud, blip that pegs the meters in SONAR and kills any further sound until after closing and reopening SONAR. I have occasionally seen this issue in the past with other plugins that seem to have issues related to mono versus stereo interleave on tracks, though I haven't seen it in a long time now (PSP MixTreble 2 was one I used to see this on fairly frequently -- it really only liked stereo at that point). In the course of playing with Neutron for an hour or so last night I saw this issue multiple times, and it basically made working with Neutron for an extended period impractical (i.e. on my system and the project I'm using, which is 64-bit audio engine and 44.1 kHz -- all softsynths except one vocal track, which was mono but set to stereo interleave). Tonight I tried it on the same project, but with Neutron only on a single softsynth track (NI Massive) and got the same issue fairly early, just playing the track after having run the Track Analyst to get it to set the processing.
The second is that, after tonight's issue with the blip and killing SONAR's audio, I saved the project with Neutron still in it, hoping to preserve the settings it calculated to listen after reloading. However, when I reloaded the project, SONAR crashed. I tried it multiple times with the same result. I even tried loading the project with the selective plugin loading, but, even before I got to the point where I'd have loaded or not loaded Neutron, SONAR crashed again. I had to work around it by going back to a version of the project I'd saved prior to adding Neutron.
In the little bits of time I was playing with Neutron last night, mostly trying it on the vocal track, bypassing all other plugins I had on that track to see what it would do as the sole processing on the track (there were still sends to other aux effects and one effect on the mix bus), I did feel the job it did on the vocal from Track Analyst was respectable. I didn't do enough of a side-by-side comparison with the other processing I'd had on the track to see if I'd have been likely to have ended up using Neutron or the chain I'd had on there, and it would almost certainly have depended on how things worked out with the rest of the mix, but, for what I had, Neutron's calculated processing sat fairly nicely in the mix.
The thing that really gets me excited about Neutron is the combination of Track Analyst (to calculate EQ and multiband nodes based on the content of the track plus its built-in "knowledge") and the masking indicator. I'm decidedly not an EQ pro in the sense of hearing something and knowing where to set EQ. I tend to use visual tools to help me figure that stuff out, but it can be pretty tedious once you get beyond a few tracks. I'm hoping Neutron will be a major timesaver on that front, whether I can use was it does directly or just use it as a starting point.
Hopefully iZotope will be able to get to the bottom of the issue quickly.