I'm using a UFX via USB, and I used a FF800 before that. I get that message all the time.
I haven't rigorously tested it to be sure, but it seems to happen when bit depth or sample frequency change. That is, if I'm working on a project in 96/24 and switch to 48/24 or 44.1/16, there's a pause, some clicks, and often the message appears.
I'm using the latest drivers and firmware.