Need more information Glenn.
Is it every time you stop? (Autosave kicking in?)
Is it when you make a few changes?
Is it when you save?
Or combinations of the above?
Are your 40 tracks all audio or a combination of Audio/Midi?
If there's any Midi, what synths, soft or external are you driving?
Also, re your signature - do you mean your rig is operating with 2Gb of RAM?
If so, I would suggest this is what's bottlenecking your CPU