stevec
I tend to leave it unchecked for playback, but do use the option during Export just in case there's some combination of tracks, synths, FX, routing, etc, that may benefit... even if it's barely noticeable. Why not?
Yeah, that's what I do as well. Don't know if there's a significant difference in processing power with it checked vs unchecked and I don't know if I can even tell the difference... but I do it for my dog.