Normally it is best to have an interface with more than one stereo output. You sort of have a 3/4 option but this is SPDIF. It would work to monitor with 3/4 if you have control room monitoring that is SPDIF capable. Lots of monitors do.
The reason is you don't want your whole mix running out to the amp so you need to send just the guitar track to which ever output you are using. In your case this can only be 1 or 2.
Every track has an output option. This defaults to your Master or to the first pair of outputs ( 1/2) The Master defaults to 1/2 as well.
SO if you have the option of using the SPDIF to your monitoring system then hook the coaxial cable up and assign the MAster to 3/4. It probably is marked as "3/4 Digital Output"
If you don't have the SPDIF option then use the 1/2 output, but make sure the track you are recording into is not set for input echo.
If shutting off input echo does not stop the feedback loop then assign the track to output 3/4. In other words, anything but 1/2.