It seems to be an "iffy" way to go. For some it works OK, others have reported problems (on other forums). Probably depends on how loaded the USB bus is.
When I was troubleshooting, what turned out to be a USB 3.0 compatibility problem with my MOTU 896Mk3 Hybrid, I tried external hubs (both a USB 2.0 and 3.0) and there wasn't any difference compared to connecting the unit direct. Thus if I would have got the MOTU to work with a PC USB 3.0 port I would have left it with the hub. Unfortunately the MOTU didn't work with the PC USB 3.0 port regardless of what type of external hub was used.