I opened a project that has Guitar Rig 5 between some UAD-2 plug-ins.  A warning pops up that says there will be a latency on that track.  There certainly is a delay.  The other problem is the plug-ins don't sound the same as in X2.  I tried resetting and rescanning the vst folders.
Any ideas?  X2 has no latency on that same track.  I haven't tried creating a new project to see if the plug-ins sound different.

What happens if you delete guitar rig? is the latency still there?
X2 has issues with waves plugs in between uad-2 plugs...
 

I changed to ASIO drivers and there is no noticeable latency anymore.  I'm using two delays, the Cooper Time Cube and the EP-34 Tape echo.  The tape echo is only working on the left channel.  I converted the file to mono with same results.  Strange.  Anytime I make a change to one of the plug-ins that warning pops up.  That is beginning to annoy me.  Guess I'll finish the song in X2.  I haven't put any waves between uad so I never ran across that problem in X2.

GTex62
I changed to ASIO drivers and there is no noticeable latency anymore.  I'm using two delays, the Cooper Time Cube and the EP-34 Tape echo.  The tape echo is only working on the left channel.  I converted the file to mono with same results.  Strange.  Anytime I make a change to one of the plug-ins that warning pops up.  That is beginning to annoy me.  Guess I'll finish the song in X2.  I haven't put any waves between uad so I never ran across that problem in X2.

Are you to date with UAD?
 
I'm having a problem that I'll see later tonight if updating to the latest solves the problem

I'm getting a similar message upon project load. And it sounds like the UAD plugins are bypassed and there is no activity on the plugin GUI. Sonar does not indicate that the plugs are disabled.
 
If I then randomly load a new UAD plugin, I get the message about a non UAD plugin between UAD plugs and potential latency, BUT, the UAD plugs start working.
 
I seem to remember this behavior between SONAR and UAD before

djtrailmixxx
If I then randomly load a new UAD plugin, I get the message about a non UAD plugin between UAD plugs and potential latency, BUT, the UAD plugs start working.

Whenever I got that message in X2a it was true becuase eventually I'd find something like:
Slate VCC
UAD LA-2A
Fabfilter Pro L
 

Same problems here too .. Iv'e been using UAD 2 plugins for about three months on Sonar X2a and never got that latency message ever . And the plugins had no noticeable latency , Even mixed between other brand plugs with no problems . In X3 I did a lot of plugin manager tweaks and Aud ini. file changes with no luck ....I had two different Recording sessions today and did them on X2a .....Everything was fine.   I really want to use X3 , its great other than the UAD issue. I'm going to tweak some more things tonight. I will report any good results.

Same issue here with X2a and UA plugins.

As long as each FX bin has contiguous UA plugins, there is no issue.

I think it's the UA plugin manager.
It gets confused when you sandwich other plugins inbetween its plugins.

Maybe it has to do with reporting latencies to the DAW?

... it's a mystery at this point...

It seems to only happen in the buss section and not the track section . If I manually bypass the plugin and press the button on each UAD plugin again it goes back in sync . If I hit E or global bypass and re enable them , Some of the UAD plugins won't work at all until I manually hit that little round blue button on the left side of the plugin. That would take to long every time you open up a large project. But at least I can sync the UAD stuff back up and use.   X2a has not given me any problems ,,,so It might be a setting somewhere on X3 or VST3 side effects.

bump