Oh yes definitely. My typical songs consist of;
1. A bass track (audio)
2. A drums track (audio)
3. An extra drums track ( audio)
4. A harmony part track (audio)
5. Another harmony part track (audio)
6. Miscallaneous ( audio)
7. A live input for vocals ( fx type sounds)
8. Maschine (played and edited live, so midi)
Everything is pre split into sections/loops of course, so I can jump to the chorus or verse of a given song at any time, mix the bass in or out, etcetera. Keeping the track order between songs means I can select an entire song from the browser, plunk it in, and have roughly the same mix. While everything keeps playing. It's super flexible this way and I usually don't really need to edit midi synth parts while performing live ( I also play keys live), I tend to focus more on fx and mix, dj-ish.