What can I say. Experimentation is good, and so trying out the CE in various places is important.
But if you want to use the CE in the way it was intended, by it's developer, Overloud, then put it last in the chain.
I have not discussed it with Danny, although I know he is not a fan, but I have talked to Overloud, and been involved in threads in which Noel and Craig Anderton have suggested using it last. I have also watched Brandon and Seth do the same, and see that Cakewalk have always put them last. We are free to ignore them, it's up to us, but I'm prepared to take their word for it, especially Overloud, who surely had some idea about it when they programmed the module.
Just my penny's worth.
Anyway, back to wild speculation about the up an coming X3..