Are you using a lap top, then the sound card must be loaded, sometimes that throws a glitch in your audio devices under preferences
Go to preferences\ devices, does your UA25 still show up and are they checked off?
As I found with two USB ports on this computer, plug in the same device to the same port every time, such as yours audio interface or some type of MIDI controller... otherwise the devices will not respond
Then if all is blank in devices, reinstall the UA25 drivers again.....