Karhide, sounds like us RME guys think the same. RME Total Mix makes it completely easy to have a different mix of every pair of outs from the interface using TotalMix.
I know I could have done a single mix with my M-Audio if I wanted to, but I couldn't do a control room mix that differed from the drummers mix that differed from the vocalists mix (which we can do with RME TotalMix).
In this link, RME likens TotalMix to Cubase and say they used Cubase's Routing Logic as a jumping off place for TotalMix.
It makes me wonder how this same question would be answered on a Cubase Forum.
Right now, I'm imagining a case where you select your output bus in Sonar and you get an entirely different set of FX, Sends, Busses, automation envelopes etc. You could have as many full mixes as you have interface output pairs. You could have things in common across all mixes or specific to certain mixes. You could copy a mix to a new output pair on your interface and go to town, then A/B the two outputs! Now, this would push the load on the PC through the Ceiling -- 10 copies of all your FX and Routing and Synths all running at the same time... haha. Wahoo!!
But, to tell the truth, I don't think I'd ever use this in Sonar if we had it. I'd just use my RME exactly as described.