Hi Tony,
Yeah, MADI + Orion is really nice. Only downside is if you have multiple different brand converters the conversion latency can cause some phase problems. Honestly, if you don't need the additional routing options and the minor latency hit from USB isn't a problem it's probably just as well to stay with the Orion running over USB. Also, MADI out of the Orion does limit you to 96khz (unless you reduce your channel count), but that's not really a problem for most folks.
OTOH, seeing 194 ins and 196 outs from my RME HDSPe MADI FX in Sonar (before you pare down the exposed I/O's) is kinda awesome :) And TotalMix really is ridiculously cool.
If you have questions about MADI with the Orion let me know and I can try to help out. There are some potential speed bumps with PT10 and some MADI cards as well.
Dean