Sure, I routinely use as many as 8 outputs with SampleTank. There is a non-obvious trick to it, however.
First, you have to tell ST how many outputs to configure. Click on the Prefs button and move the slider at the bottom of the Preferences dialog to indicate how many outputs to make available. The number is displayed in stereo pairs, e.g. 1+2, 3+4, 5+6, etc.
Next - this is the non-intuitive part - you have route the channel to the desired output pair. Under the "OUT" column there'll be "1+2" indicating that the channel's going to the first stereo pair. Put your mouse on the "1+2" and drag upward to cycle through the available outputs.