That's one of the little details that distinguishes free software from commercial products: how it handles unexpected situations such as the previously-specified IR not being found. It's possible that there's a "file not found" dialog in the background. You might be able to hit ENTER and get past it.
IF that doesn't work, follow rbh's advice above: load the project in safe mode (hold the SHIFT key down while starting), delete the plugin and save it. Then re-open it and put the plugin back in.