I've been on Windows 8 64 bit since December. I have an Acer 27" touch screen and I'm loving it.
As long as there are Widows 8 drivers for all of your hardware, I wouldn't hesitate.
I did the Windows 8 update on my DAW PC . After the update there is a function in W8 ,I think it's called "refresh". It puts a clean install of W8 on your PC and puts all of your documents in a "Windows Old" file. You will need to re-install all of your apps
I may be the lucky guy that has the magic combination in my DIY PC, but I've had zero issues.
I don't miss the start menu at all
Give the touch screen some time. The day that I connected it I was a bit disappointed. Once I got used to how it responds,it became an indispensable tool.
I do have my touch monitor mounted horizontally so that it's like a control surface. I'm sure that this adds to the experience.