I'm using Line 6 Monkey as my input and output midi device.
Line6 Monkey is not an audio device. Its a program that updates the drivers on your devices. So what is your audio interface?
Try this:
Insert - Softsynth (Select the TTS-1 which is a General MIDI synth)
Make the output of the MIDI track the TTS-1
Press play.
If you have an external synth keyboard or rack module, then set the output of the MIDI track to your MIDI interface instead of the softsynth.