Been using w8 for about a year now. I have it installed on 5 computers in the office/house.
And a bunch of clients have upgraded/purchased new machines.
As for tweaks: There are a number of scheduled tasks that can interfere with happiness.
The defragger starting late wed night was an interruption that was not obvious at first. Definitely disabled now.
The computer assessment tasks should be disabled.
Windows updates disabled.
Only auto update I have running is for the anti-malware application.
Change all defaults to use the desktop versions: PDF reader (I use Adobe reader), windows media player,...
change the taskbar to never combine: combining adds extra clicks and time
A number of stupid windows 8 tricks are included:
cannot copy shortcuts from taskbar to desktop. So, have to right click on the start-wall icon and choose to open file location and then copy a shortcut to the desktop.
changing some of the wireless profile data requires command line knowledge (e.g. changing encryption type) This is the best stupidity so far.
can only add/change user password on with the user panel accessed from the charms bar
My music computer shows nearly 90 icons on the start-wall when I choose to show all apps. This is a way stupid approach compared to the start menu.
I used the windows explorer to add folders to the "start menu" folders to have the start-wall not be so arbitrary. I have a shortcut on the desktop to open the start menu folders.
Also, I have folders on the desktop containing shortcuts by need: audio tools, windows tools, instruments, documents (links to the server computer that holds all the support docs),....