Have your audio interface drivers been updated without your realising? Sometimes the latest drivers aren't always the greatest. If they have roll back and see if that helps. I had similar issues once and that was the fix for me (still is).
Having said that if nothing has changed it seems very strange to suddenly see a changed reported latency with exactly the same settings, something must have changed. Is MS Wavetable enabled in MIDI devices? If so disable it - I have known that to cause all sorts of wierd seemingly unrelated issues.