Yeah - I disable that after any new plugs, and in fact altogether now.
My startup is really fast.
If I install anything new now, I just run it from the Plugin Manager 'Scan Vsts' button opposite the 'Options' button.
Then I'm already in the same window to add that new plugin into what I call 'My Layout' instead of using the Default plugin one.
Other than an older, slower computer, slow startups would be signs of troubles that would warrant looking into for sure - like unecessary background programs, etc.