In my workflow, particularly for drums, I use separate clips for separate elements of the drums, that way I can quickly change the kick/snare pattern from one part to another without changing the hi-hats, for example.
When I was doing dubstep-like automation for a synth track, I would also have separate and overlapping midi tracks, one for the midi notes, one for filter automation, one for pitch automation, etc. That way it is very easy for me to move around the automations without changing the notes.
However, clip locking seems to work, I never used or knew about that feature. Thanks swamptooth!