Depends on what I'm doing.
I love Keith Richards' early 70s sound (Tele/Fender Twin/ Something small & dirty).
Mark Knopfler's electric sound on Sultans of Swing is pretty slick. His acoustic sound (probably his National Resonator) on "Where do you think you're going" is killer for that dark, tense feel.
Pretty much anything Prince played was dead-on as far as tone went...
The multitude of 70s arena-rock bands did well with a simple Les Paul/ Marshall stack. Jimmy Page did just as well with a Telecaster and a Fender Champ.