a lot of that can be system dependent, gd. the pcie-424 ships with wdm/ks drivers for windows and as such - because they were specifically written for the card in question - may work well. i would gather that if they haven't updated their software for wasapi, they probably won't. i would try asio with the following qualifiers: in sonar's preferences/playback and recording uncheck "always open all devices" and try changing the "usehardwaresampleposition" setting - these can be killers if your asio drivers are not top-notch.
for wasapi:
- always work in 48 or 96khz (wasapi plays sometimes haphazardly at 44.1) because it will offload some of the processing your cpu will be doing to the audio interface. i can run 57 audio tracks with prochannel and automated eq and fx parameters without pops and clicks on my realtek audio chip while riding the bus using my laptop's battery power in wasapi mode at 144 samples.
- in preferences/configuration file you might need to see which values of "usewdmdmaforwasapi" work better on your system.
- also, in config file, set "minimizedriverstatechanges" to 3 and "threadschedulingmodel" to 2, (typically) set usehardwaresampleposition to false and dropoutmsec to around 500.
- if using wasapi, always double-check that prefs/audio/sync and caching/record latency adjustment "device" is your current device. never install asio4all if you'll be using asio mode because 4all hijacks that field and will not let you change it to your interface's drivers. you can select the interface-native drivers but if you close prefs and reopen again you'll see that asio4all is still selected.
rod - i don't know if you have any native-instruments products, but if you open any of their audio preferences you will only see options for asio or wasapi. no wdm, no mme. i use wasapi when i'm on a bus or a plane and asio when i'm back at the ranch. n-i and steinberg have been very good about future-proofing their products and they work brilliantly. and seeing that you run in 32-bit mode i would really urge you to do all recording or live work in 48 or 96khz because 44.1 is more cpu-intensive.
i've had good experience with wasapi, though it took tweaking those params in sonar to make it work ok. not a hitch at all running any n-i stuff in wasapi shared mode - even whilst watching videos on youtube. :D