A closing note to all of this.
I think doing a clean install of everything would be optimal. No doubt. HOWEVER, I'm getting smooth fast and glitch free performance with Windows 8 being installed over top of Vista 64. Keeping the OS clean and optimize has always been an ongoing thing for me here. I had very little bloat on my Vista64 OS and Windows 8 is even snappier using X2.
X2 program and project load times along with lower latency and evenly spread core usage included. If only SF8 could have been compatible with Win8, I would be very happy. But, it's not. I did find the surprise of having Johnson J-Edit work in Windows 8. That was a deal breaker for me if it didn't work, but it does. The delta 1010 Win7 drivers work great in Win8. Big relief as I really appreciate the sound, low latency and the performance specifications of this older 1010 interface. All in all, a couple user error problems with me getting this going, but I would recommend Windows 8 to others.