Plugins will cause problems if they are DXi's. 64 bit won't load them.
32 bit VSTi's will load through Bitbridge.
If the 32 bit plugs aren't on your system you will get a series of warnings stating so and you will have to re-insert their 64 bit counterparts.
I would at least install the 32 bit plugins (if that's possible) and then you can leave them be, or change then to the 64 bit versions and resave the project with a different name, as was suggested.
Steve