Thanks and thanks!
I did try the "run as administrator" trick, I gleaned that off another thread, but no dice for me. Someone suggested it only works if you also have run the INSTALL as administrator. That's seems like a lot of frickin' work just to get my screaming synth line back.
I WISH that replace synth would preserve the patch settings if it determined they were equivilant synths. I mean sheesh, worst case is you then change it.