make sure in preferences/Project/Midi that you midi sync output port and your MTC output port are assigned to only your controller(only one controller)
Make sure in Preferences/Playback and recording your currently assigned port is set to your controller(one controller)
this should help out with the crashes
EDIT:
im sorry,
scratch that message above.
i would try to open another midi track in the PRV and see if your having the same issue,it could be the midi file became corrupt.
try a few different editing procedures as well to narrow it down.let us know.